|
Toxic multinodular goiter (also known as toxic nodular goiter, toxic nodular struma, or Plummer's disease) is a multinodular goiter associated with a hyperthyroidism. It is a common cause of hyperthyroidism in which there is excess production of thyroid hormones from functionally autonomous thyroid nodules, which do not require stimulation from thyroid stimulating hormone (TSH). It is the second most common cause of hyperthyroidism (after Graves' disease) in the developed world. In countries where the population is iodine-deficient i.e. the developing world, iodine deficiency is the most common cause of hypothyroidism. (Decreased iodine leads to decreased thyroid hormone.) However, iodine deficiency can cause goitre (thyroid enlargement); within a goitre, nodules can develop. Risk factors for toxic multinodular goiter include individuals over 60 years of age and being female. ==Signs and symptoms== Symptoms of toxic multinodular goitre are similar to that of hyperthyroidism, including:〔 * heat intolerance * muscle weakness/wasting * hyperactivity * fatigue * tremor * irritability * weight loss * osteoporosis * increased appetite * non-painful goitre (swelling of the thyroid gland) * tachycardia (high heart rate - above 100 beats per minute at rest in adults) 抄文引用元・出典: フリー百科事典『 ウィキペディア（Wikipedia）』 ■ウィキペディアで「Toxic multinodular goitre」の詳細全文を読む スポンサード リンク
|